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KMID : 0191120170320020371
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Journal of Korean Medical Science
2017 Volume.32 No. 2 p.371 ~ p.376
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Neurological Complications Resulting from Non-Oral Occupational Methanol Poisoning
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Choi Ji-Hyun
Lee Seung-Keun
Gil Young-Eun
Ryu Ji-A
Jung Choi Kyung-Hee
Kim Hyun-Joo
Choi Jun-Young
Park Sun-Ah
Lee Hyang-Woon
Yun Ji-Young
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Abstract
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Methanol poisoning results in neurological complications including visual disturbances, bilateral putaminal hemorrhagic necrosis, parkinsonism, cerebral edema, coma, or seizures. Almost all reported cases of methanol poisoning are caused by oral ingestion of methanol. However, recently there was an outbreak of methanol poisoning via non-oral exposure that resulted in severe neurological complications to a few workers at industrial sites in Korea. We present 3 patients who had severe neurological complications resulting from non-oral occupational methanol poisoning. Even though initial metabolic acidosis and mental changes were improved with hemodialysis, all of the 3 patients presented optic atrophy and ataxia or parkinsonism as neurological complications resulting from methanol poisoning. In order to manage it adequately, as well as to prevent it, physicians should recognize that methanol poisoning by non-oral exposure can cause neurologic complications.
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KEYWORD
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Methanol, Poisoning, Neurological Manifestations, Metabolic Encephalopathies
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